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Placental transfer of rh-GH boosts during the third trimester as endogenous placental GH supplants pituitary secretion, but clinical importance of exogenous supplementation is unsure.

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elevated risk of growth of cancer or possibly a tumor that is definitely previously present and amplified possibility with the return of cancer or perhaps a tumor in individuals who have been treated with radiation towards the brain or head as youngsters and who formulated reduced growth hormone difficulties.

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